Selected Therapeutic Areas
CHEPLAPHARM offers a diversified product portfolio. Please find below a number of prescription drugs of selected therapeutic areas.
Insomnia is one of the most common sleep disorders characterized by difficulty falling and/or staying asleep with reduced quality, duration and restfulness of sleep. »
The worldwide marketed and well-established medicinal product ROHYPNOL® with its active ingredient Flunitrazepam belongs to the group of benzodiazepines. Benzodiazepines are centrally depressant psychotropic drugs with anxiolytic, anticonvulsant, sedative and sleep-inducing properties. ROHYPNOL® is available as film-coated tablet containing 1 mg Flunitrazepam and indicated in short-term treatment of insomnia. It is subject to medicinal prescription (mostly via special narcotic prescription).
For therapeutic purposes, antidotes are generally used in cases of poisoning, medication overdose or exposure to industrial or other toxicological agents to minimize or compensate the mostly life-threatening reactions. »
The active ingredient of ANEXATE® is Flumazenil. As benzodiazepine antagonist, ANEXATE® acts as an antidote to drugs of the benzodiazepine class and is used in clinical settings for reversal of benzodiazepine sedation/ overdose.
Leukemia is a type of cancer affecting the hematopoietic system and is caused by autonomic proliferation of abnormal white blood cells (leukocytes) and their accumulation in the bone marrow. »
VESANOID® contains as active ingredient Tretinoin, a natural derivative of vitamin A. According to international clinical guidelines, VESANOID® represents an obligate part in the treatment of Acute Promeylocytic Leukemia (APL). The introduction of Tretinoin (VESANOID®) in APL treatment has transformed this leukemia type from very fatal to highly curable. Therefore, the active ingredient Tretinoin was included in the WHO (World Health Organization) list of essential medicines and exhibits in Europe unique selling proposition.
Important disorders belonging to the hepatobiliary system pose Cholelithiasis and Primary Biliary Cirrhosis (PBC). Cholelithiasis involves the presence of gallstones, which are concretions of bile components that form in the biliary tract and may often be associated with Acute Cholecystitis. »
The medicinal products DEURSIL® / DE-URSIL® / URSOLVAN® possess as common active ingredient Ursodeoxycholic acid (UDCA), a natural bile acid occurring only to a minor degree in human being. The products are used for treatment of several hepatic and biliary disorders, e.g. cholesterol gallstones. According to e.g. European clinical guidelines, the active substance UDCA is recommended as first line treatment of Primary Biliary Cirrhosis (PBC).
Alcohol is the most widely used and abused drug in the world, and alcohol use disorders lead to tremendous economic consequences for healthcare systems. »
The active substance of the medicinal product is Clomethiazole, a short-acting hypnotic with sedative and anticonvulsant properties. According to several European guidelines, besides benzodiazepines, Clomethiazole is recommended as frontline-treatment concerning the therapy of acute alcohol withdrawal syndromes and delirium tremens. Additionally, DISTRANEURIN® / HEMINEVRIN® is also indicated in the management of restlessness and agitation in the elderly for clinical settings as well as in the treatment of severe insomnia if other therapies are not applicable. The product exhibits with its active substance Clomethiazole unique selling proposition on a global level.
INDURATIO PENIS PLASTICA
Induratio penis plastica (IPP, also called Peyronie’s disease) is a connective tissue disorder involving the growth of fibrous plaques in the soft tissue of the penis affecting an estimated 5% of men. »
The medicinal product POTABA-GLENWOOD® with its active substance Potassium 4-aminobenzoate is indicated in the treatment of Peyronie´s disease (Induratio penis plastic, IPP). According to Clinical Guideline on Penile Curvature of European Association of Urology, Potassium 4-aminobenzoate shows the best evidence-based efficacy of oral available medications in the treatment of IPP. POTABA-GLENWOOD® with its active substance Potassium 4-aminobenzoate exhibits worldwide unique selling proposition for the registered indication of IPP.